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Changho Han

9PUBLICATIONS
18CO-AUTHORS
Biomolecular modelling and designPharmaceutical delivery technologiesCharacterisation of biological macromoleculesMolecular targetsCheminformatics and quantitative structure-activity relationships
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Journal

Publications (9)

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|Jul 16, 2025
Discovery of a Novel sp<sup>3</sup>‑Rich M<sub>1</sub> Positive Allosteric Modulators (PAMs) Chemotype via Scaffold Hopping.

Joseph D Bungard, Paul Spearing, Yu Nishio

|May 14, 2025
Discovery of Thieno[3,2-<i>b</i>]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Katherine E Crocker, Scott H Henderson, Rory A Capstick

|Mar 25, 2025
Application of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422.

Julie L Engers, Jinming Li, Changho Han

|Dec 11, 2024
Discovery of VU0467319: an M<sub>1</sub> Positive Allosteric Modulator Candidate That Advanced into Clinical Trials.

Michael S Poslunsey, Michael R Wood, Changho Han

|Aug 06, 2024
Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M<sub>5</sub> Muscarinic Acetylcholine Receptor.

Jinming Li, Douglas L Orsi, Julie L Engers

|Dec 12, 2023
Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.

Kevin B Teuscher, Jonathan J Mills, Jianhua Tian

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Frequent Collaborators

8 joint publications

Craig W Lindsley

5 joint publications

Alice L Rodriguez

4 joint publications

Julie L Engers

2 joint publications

Douglas L Orsi

2 joint publications

Madeline F Long

1 joint publications

Aaron M Bender

1 joint publications

Laura B Teal

1 joint publications

Daniel J Foster

1 joint publications

Kevin B Teuscher

1 joint publications

Jonathan J Mills

Frequent Collaborators

8 joint publications

Craig W Lindsley

5 joint publications

Alice L Rodriguez

4 joint publications

Julie L Engers

2 joint publications

Douglas L Orsi

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