Changho Han
9PUBLICATIONS
18CO-AUTHORS
Get your video featured.
Publish with JoVEGet your video featured.
Publish with JoVE
Publications (9)
Sort by Publication Date:
|Jul 16, 2025
Discovery of a Novel sp3‑Rich M1 Positive Allosteric Modulators (PAMs) Chemotype via Scaffold Hopping.Joseph D Bungard, Paul Spearing, Yu Nishio
|May 14, 2025
Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.Katherine E Crocker, Scott H Henderson, Rory A Capstick
|Mar 25, 2025
Application of Deuterium in an M1 Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422.Julie L Engers, Jinming Li, Changho Han
|Dec 11, 2024
Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials.Michael S Poslunsey, Michael R Wood, Changho Han
|Aug 06, 2024
Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor.Jinming Li, Douglas L Orsi, Julie L Engers
|Dec 12, 2023
Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.Kevin B Teuscher, Jonathan J Mills, Jianhua Tian
Pageof 2
Frequent Collaborators
8 joint publications
Craig W Lindsley
5 joint publications
Alice L Rodriguez
4 joint publications
Julie L Engers
2 joint publications
Douglas L Orsi
2 joint publications
Madeline F Long
1 joint publications
Aaron M Bender
1 joint publications
Laura B Teal
1 joint publications
Daniel J Foster
1 joint publications
Kevin B Teuscher
1 joint publications
Jonathan J Mills
