Alice L Rodriguez

18PUBLICATIONS
22CO-AUTHORS
Characterisation of biological macromoleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designBiologically active moleculesPharmaceutical delivery technologies
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (18)

|Jul 16, 2026
Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

|Jul 07, 2026
Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

|Jun 23, 2026
Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

|Feb 05, 2026
Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.

Daniel H Haymer, Renn A Duncan, Alice L Rodriguez

|Jan 26, 2026
Discovery of 7-(Pyridin-3-yl)thieno[3,2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Scott H Henderson, Anna E Ringuette, David L Whomble

|Jan 25, 2026
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy.

Alison R Gregro, Charlotte Park, Madeline F Long

Pageof 3

Frequent Collaborators

15 joint publications

Craig W Lindsley

9 joint publications

Colleen M Niswender

7 joint publications

Kayla J Temple

6 joint publications

Julie L Engers