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Alice L Rodriguez

17PUBLICATIONS
21CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designBiologically active moleculesCharacterisation of biological macromoleculesPharmaceutical delivery technologies
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Journal

Publications (17)

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|Jul 07, 2026
Discovery of VU6077564: A Selective M<sub>1</sub> Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

|Jun 23, 2026
Discovery of VU6066098: A Selective and CNS-Penetrant mGlu<sub>2</sub> NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

|Feb 05, 2026
Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.

Daniel H Haymer, Renn A Duncan, Alice L Rodriguez

|Jan 26, 2026
Discovery of 7-(Pyridin-3-yl)thieno[3,2-<i>b</i>]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Scott H Henderson, Anna E Ringuette, David L Whomble

|Jan 25, 2026
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust <i>In Vivo</i> Efficacy.

Alison R Gregro, Charlotte Park, Madeline F Long

|Jul 21, 2025
Profiling the Impact of mGlu<sub>7</sub>/Elfn1 Protein Interactions on the Pharmacology of mGlu<sub>7</sub> Allosteric Modulators.

Xia Lei, Zixiu Xiang, Alice L Rodriguez

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Frequent Collaborators

14 joint publications

Craig W Lindsley

8 joint publications

Colleen M Niswender

6 joint publications

Kayla J Temple

6 joint publications

Julie L Engers

5 joint publications

Madeline F Long

5 joint publications

Changho Han

2 joint publications

Vincent B Luscombe

2 joint publications

Scott H Henderson

2 joint publications

Zixiu Xiang

1 joint publications

Douglas L Orsi

Frequent Collaborators

14 joint publications

Craig W Lindsley

8 joint publications

Colleen M Niswender

6 joint publications

Kayla J Temple

6 joint publications

Julie L Engers