Alice L Rodriguez

19PUBLICATIONS
23CO-AUTHORS
Biomolecular modelling and designCharacterisation of biological macromoleculesCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesPharmaceutical delivery technologies
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Publications (19)

|Sep 15, 2026
De Novo Design in an M1 Positive Allosteric Modulator Backup Program: The Discovery of VU6069863.

|Jul 16, 2026
Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

|Jul 07, 2026
Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

|Jun 23, 2026
Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

|Feb 05, 2026
Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.

Daniel H Haymer, Renn A Duncan, Alice L Rodriguez

|Jan 26, 2026
Discovery of 7-(Pyridin-3-yl)thieno[3,2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Scott H Henderson, Anna E Ringuette, David L Whomble

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Frequent Collaborators

16 joint publications

Craig W Lindsley

10 joint publications

Colleen M Niswender

7 joint publications

Kayla J Temple

7 joint publications

Julie L Engers