Kayla J Temple

8PUBLICATIONS
13CO-AUTHORS
Characterisation of biological macromoleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (8)

|Jul 16, 2026
Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

|Jan 26, 2026
Discovery of 7-(Pyridin-3-yl)thieno[3,2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Scott H Henderson, Anna E Ringuette, David L Whomble

|Jan 25, 2026
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy.

Alison R Gregro, Charlotte Park, Madeline F Long

|Sep 19, 2025
Highly Potent and Subtype-Selective Sperm-Specific Potassium Channel SLO3 Inhibitors Display High Tissue Exposure in the Murine Female Reproductive Tract.

Kayla J Temple, Ping Li, Hallie G McKinnie

|May 14, 2025
Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Katherine E Crocker, Scott H Henderson, Rory A Capstick

|Dec 18, 2024
Discovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.

Elizabeth S Childress, Rory A Capstick, Katherine E Crocker

Pageof 2

Frequent Collaborators

7 joint publications

Alice L Rodriguez

7 joint publications

Craig W Lindsley

3 joint publications

Colleen M Niswender

2 joint publications

Madeline F Long