Ellen Sapp

5PUBLICATIONS
28CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Medical molecular engineering of nucleic acids and proteinsNanoscale characterisationComputational neuroscience (incl. mathematical neuroscience and theoretical neuroscience)
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Publications (5)

|Aug 12, 2026
Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice.

|Sep 10, 2025
Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregation.

Ellen Sapp, Adel Boudi, Andrew Iwanowicz

|Sep 05, 2025
ESC derived human cortical neurons harboring the NACC1 c.892C > T p.R298W missense mutation exhibit molecular differences from controls that influence neuronal maturation.

Mark Deehan, Ellen Sapp, Andrew Iwanowicz

|May 22, 2024
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo.

Sarah Allen, Daniel O'Reilly, Rachael Miller

|Feb 22, 2024
Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction.

Mark A Deehan, Josine M Kothuis, Ellen Sapp

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Frequent Collaborators

3 joint publications

Anastasia Khvorova

2 joint publications

Daniel O'Reilly

2 joint publications

Rachael Miller

2 joint publications

Ashley Summers