Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Ashley Summers

7PUBLICATIONS
52CO-AUTHORS
Gene and molecular therapyMolecular targetsBiologically active moleculesMedical molecular engineering of nucleic acids and proteins
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

Sort by Publication Date:
|Feb 03, 2026
Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine model.

Hassan H Fakih, Mohammad Zain Ui Abideen, Mohamad Omar Rachid

|Nov 14, 2025
Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.

Ella W Mathews, Sydney R Coffey, Annette Gärtner

|May 02, 2025
Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model.

Vignesh N Hariharan, Ashley Summers, Amy E Clipperton-Allen

|Aug 01, 2024
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones.

Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi

|May 22, 2024
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs <i>in vivo</i>.

Sarah Allen, Daniel O'Reilly, Rachael Miller

|Nov 05, 2023
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.

Qi Tang, Hassan H Fakih, Mohammad Zain Ui Abideen

Pageof 2

Frequent Collaborators

7 joint publications

Anastasia Khvorova

5 joint publications

Qi Tang

4 joint publications

Vignesh Narayan Hariharan

4 joint publications

Nicholas McHugh

4 joint publications

Julia F Alterman

3 joint publications

Rachael Miller

3 joint publications

Hassan H Fakih

3 joint publications

Raymond C Furgal

2 joint publications

Chantal M Ferguson

2 joint publications

Bruno M D C Godinho

Frequent Collaborators

7 joint publications

Anastasia Khvorova

5 joint publications

Qi Tang

4 joint publications

Vignesh Narayan Hariharan

4 joint publications

Nicholas McHugh

Top Related Videos

Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart
09:12

Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart

Published on : Jul 29, 2018

8.6K
Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
07:08

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on : Feb 27, 2018

10.0K
Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome
11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Published on : Mar 02, 2018

7.2K
See more related videos

Top Related Videos

Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart
09:12

Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart

Published on : Jul 29, 2018

8.6K
Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
07:08

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on : Feb 27, 2018

10.0K
Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome
11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Published on : Mar 02, 2018

7.2K
See more related videos