Nandini C Patel

7PUBLICATIONS
61CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsProteins and peptidesChemical engineering designPharmaceutical delivery technologiesInfectious diseases
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Publications (7)

|Feb 28, 2025
Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.

Jamison B Tuttle, Christophe Allais, Charlotte M N Allerton

|Aug 30, 2024
Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model.

Michelle R Garnsey, Matthew C Robinson, Luong T Nguyen

|Jun 07, 2024
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.

Martin Pettersson, Douglas S Johnson, John M Humphrey

|Apr 30, 2024
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19.

Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner

|Feb 14, 2022
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans.

Heather Eng, Alyssa L Dantonio, Eugene P Kadar

|Nov 02, 2021
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.

Dafydd R Owen, Charlotte M N Allerton, Annaliesa S Anderson

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