Amit S Kalgutkar

37PUBLICATIONS
138CO-AUTHORS
Nanotoxicology, health and safetyEnvironmental biogeochemistryWastewater treatment processesCheminformatics and quantitative structure-activity relationshipsMolecular medicine
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Publications (37)

|Aug 01, 2026
The 5'-Isobutyryl Ester Prodrug of 4'-Thiouridine Inhibits SARS-CoV‑2 Replication in Culture and in a Syrian Hamster Infection Model.

|Nov 06, 2025
Studies addressing potential bioactivation and genotoxicity liabilities of the N-nitroso derivative of the antidepressant paroxetine.

Carley J S Heck, Heather Eng, Jennifer R Cheung

|Sep 25, 2025
Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Ervogastat, a Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitor, and Clesacostat, an Acetyl-CoA Carboxylase (ACC) Inhibitor.

Manoli Vourvahis, Arthur J Bergman, Adam G Ogden

|Feb 28, 2025
Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.

Jamison B Tuttle, Christophe Allais, Charlotte M N Allerton

|Nov 19, 2024
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948.

Kevin J Filipski, Luis A Martinez-Alsina, Matthew R Reese

|Aug 30, 2024
Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model.

Michelle R Garnsey, Matthew C Robinson, Luong T Nguyen

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Frequent Collaborators

7 joint publications

Heather Eng

5 joint publications

Upendra A Argikar

5 joint publications

Nandini C Patel

5 joint publications

Carley J S Heck