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Heather Eng

13PUBLICATIONS

95CO-AUTHORS

Epigenetics (incl. genome methylation and epigenomics)Proteins and peptidesGene and molecular therapyVeterinary pharmacologyCheminformatics and quantitative structure-activity relationships

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Publications (13)

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|Jan 02, 2025

Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants.

Michelle R Garnsey, Yang Wang, David J Edmonds

|Aug 30, 2024

Discovery of SARS-CoV-2 papain-like protease (PL<sup>pro</sup>) inhibitors with efficacy in a murine infection model.

Michelle R Garnsey, Matthew C Robinson, Luong T Nguyen

|Aug 01, 2024

Development of a sensitive LC-MS/MS assay to support human microdose study for an oral agonist of the GLP-1 receptor.

Eugene P Kadar, Heather Eng, Amit S Kalgutkar

|Feb 21, 2023

Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir.

Siennah R Greenfield, Heather Eng, Qingyi Yang

|Jul 01, 2022

Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.

Angela C Doran, Woodrow Burchett, Connor Landers

|Jun 09, 2022

Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.

Ravi Shankar P Singh, Gregory S Walker, Eugene P Kadar

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Frequent Collaborators

7 joint publications

Amit S Kalgutkar

6 joint publications

R Scott Obach

3 joint publications

Britton Boras

3 joint publications

Ravi Shankar P Singh

3 joint publications

Eugene P Kadar

3 joint publications

Li Di

3 joint publications

Emi Kimoto

3 joint publications

Nandini C Patel

3 joint publications

Matthew A Cerny

2 joint publications

Rhys M Jones

Frequent Collaborators

7 joint publications

Amit S Kalgutkar

6 joint publications

R Scott Obach

3 joint publications

Britton Boras

3 joint publications

Ravi Shankar P Singh

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