R Scott Obach
10PUBLICATIONS
55CO-AUTHORS
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Publications (10)
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|Jun 09, 2022
Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.Ravi Shankar P Singh, Gregory S Walker, Eugene P Kadar
|Feb 14, 2022
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans.Heather Eng, Alyssa L Dantonio, Eugene P Kadar
|Nov 02, 2021
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.Dafydd R Owen, Charlotte M N Allerton, Annaliesa S Anderson
|Jul 30, 2021
Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes.Elaine Tseng, Heather Eng, Jian Lin
|Apr 03, 2021
Cytochrome P450 3A Time-Dependent Inhibition Assays Are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants.Heather Eng, Elaine Tseng, Matthew A Cerny
|Sep 16, 2020
Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.Britton Boras, Rhys M Jones, Brandon J Anson
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Frequent Collaborators
6 joint publications
Heather Eng
3 joint publications
Ravi Shankar P Singh
3 joint publications
Amit S Kalgutkar
2 joint publications
Emi Kimoto
2 joint publications
Eugene P Kadar
2 joint publications
Dafydd R Owen
2 joint publications
Li Di
2 joint publications
Theunis C Goosen
2 joint publications
Claire Steppan
2 joint publications
Britton Boras
