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Michael Siu

10PUBLICATIONS

32CO-AUTHORS

Molecular targetsNeural engineeringImmunogenetics (incl. genetic immunology)Toxicology (incl. clinical toxicology)Cheminformatics and quantitative structure-activity relationships

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Publications (10)

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|Mar 02, 2026

Discovery and Optimization of a Potent, Efficacious, and Brain-Penetrant Inhibitor of KRAS G12C.

Matthew L Landry, Sushant Malhotra, Maureen Beresini

|Oct 30, 2025

Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases.

Snahel Patel, Huifen Chen, Eugene Varfolomeev

|Sep 18, 2024

Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1.

John C Tellis, BinQing Wei, Michael Siu

|Nov 15, 2021

Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.

Dennis X Hu, Snahel Patel, Huifen Chen

|May 31, 2021

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor.

Malcolm P Huestis, Matthew R Durk, Charles Eigenbrot

|Mar 29, 2021

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3<i>H</i>)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor.

Malcolm P Huestis, Darlene Dela Cruz, Antonio G DiPasquale

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Frequent Collaborators

3 joint publications

Snahel Patel

2 joint publications

Huifen Chen

2 joint publications

Dennis X Hu

2 joint publications

Malcolm P Huestis

1 joint publications

Hans E Purkey

1 joint publications

William J Meilandt

1 joint publications

Han Lin

1 joint publications

Alvin Gogineni

1 joint publications

Seung-Hye Lee

1 joint publications

Janice Maloney

Frequent Collaborators

3 joint publications

Snahel Patel

2 joint publications

Huifen Chen

2 joint publications

Dennis X Hu

2 joint publications

Malcolm P Huestis

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