Michael Siu
10PUBLICATIONS
32CO-AUTHORS
Get your video featured.
Publish with JoVEGet your video featured.
Publish with JoVE
Publications (10)
Sort by Publication Date:
|Mar 02, 2026
Discovery and Optimization of a Potent, Efficacious, and Brain-Penetrant Inhibitor of KRAS G12C.Matthew L Landry, Sushant Malhotra, Maureen Beresini
|Oct 30, 2025
Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases.Snahel Patel, Huifen Chen, Eugene Varfolomeev
|Sep 18, 2024
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1.John C Tellis, BinQing Wei, Michael Siu
|Nov 15, 2021
Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.Dennis X Hu, Snahel Patel, Huifen Chen
|May 31, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor.Malcolm P Huestis, Matthew R Durk, Charles Eigenbrot
|Mar 29, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3H)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor.Malcolm P Huestis, Darlene Dela Cruz, Antonio G DiPasquale
Pageof 2
Frequent Collaborators
3 joint publications
Snahel Patel
2 joint publications
Huifen Chen
2 joint publications
Dennis X Hu
2 joint publications
Malcolm P Huestis
1 joint publications
Hans E Purkey
1 joint publications
William J Meilandt
1 joint publications
Han Lin
1 joint publications
Alvin Gogineni
1 joint publications
Seung-Hye Lee
1 joint publications
Janice Maloney
