Simona Cotesta
5PUBLICATIONS
36CO-AUTHORS
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Publications (5)
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|Jul 10, 2025
Promise and Challenge of β-Lactone Electrophiles to Target Aspartate 12 of Mutant KRAS<sup>G12D</sup>.Balázs Budai, Andrea Vaupel, Callum J Dickson
|Jun 09, 2023
Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension.Duncan E Shaw, Nichola Smith, Rene Beerli
|Nov 18, 2022
JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS<sup>G12C</sup> for the Treatment of Solid Tumors.Edwige Lorthiois, Marc Gerspacher, Kim S Beyer
|Apr 11, 2022
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.Andreas Weiss, Edwige Lorthiois, Louise Barys
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Frequent Collaborators
4 joint publications
Kim S Beyer
4 joint publications
Rainer Wilcken
4 joint publications
Nils Ostermann
3 joint publications
Claudio Bomio-Confaglia
3 joint publications
Andrea Vaupel
2 joint publications
Andreas Weiss
2 joint publications
Daniel A Guthy
2 joint publications
Hans Voshol
2 joint publications
Johannes Ottl
2 joint publications
Rowan Stringer