Nils Ostermann

7PUBLICATIONS
56CO-AUTHORS
Biomolecular modelling and designMolecular targetsMedical mycology
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Publications (7)

|May 19, 2026
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation.

|Dec 02, 2025
Identification and characterization of binders to a cryptic and functional pocket in KRAS.

Kim S Beyer, Jessica Klein, Stéphanie Katz

|Jul 10, 2025
Promise and Challenge of β-Lactone Electrophiles to Target Aspartate 12 of Mutant KRAS<sup>G12D</sup>.

Balázs Budai, Andrea Vaupel, Callum J Dickson

|Mar 31, 2025
Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras.

Charles W Parry, Francesca Pellicano, Alexander W Schüttelkopf

|Mar 08, 2023
Design and Biochemical Characterization of Peptidic Inhibitors of the Myb/p300 Interaction.

Matthew Jones, Philipp Grosche, Andreas Floersheimer

|Nov 18, 2022
JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS<sup>G12C</sup> for the Treatment of Solid Tumors.

Edwige Lorthiois, Marc Gerspacher, Kim S Beyer

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Frequent Collaborators

6 joint publications

Kim S Beyer

4 joint publications

Simona Cotesta

4 joint publications

Rainer Wilcken

3 joint publications

Andrea Vaupel