Christopher M Adams
6PUBLICATIONS
12CO-AUTHORS
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Publications (6)
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|Jul 15, 2020
Understanding metabolism related differences in ocular efficacy of MGV354.Jennifer L Dumouchel, Upendra A Argikar, Christopher M Adams
|Jun 20, 2020
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.Edwige Lorthiois, James Roache, David Barnes-Seeman
|Feb 20, 2020
Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.Nello Mainolfi, Takeru Ehara, Rajeshri G Karki
|Apr 18, 2019
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.Rajeshri G Karki, James Powers, Nello Mainolfi
|Mar 03, 2018
The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma.Takeru Ehara, Christopher M Adams, Doug Bevan
|Feb 06, 2018
The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration.Christopher M Adams, Karen Anderson, Gerald Artman
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Frequent Collaborators
3 joint publications
Rajeshri G Karki
3 joint publications
Upendra A Argikar
2 joint publications
Edwige Lorthiois
2 joint publications
Takeru Ehara
1 joint publications
Anna Vulpetti
1 joint publications
Aengus Mac Sweeney
1 joint publications
Finton Sirockin
1 joint publications
James Roache
1 joint publications
Eva Altmann
1 joint publications
Jennifer L Dumouchel
