Edwige Lorthiois
4PUBLICATIONS
20CO-AUTHORS
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Publications (4)
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|Nov 18, 2022
JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors.Edwige Lorthiois, Marc Gerspacher, Kim S Beyer
|Jun 20, 2020
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.Edwige Lorthiois, James Roache, David Barnes-Seeman
|Apr 18, 2019
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.Rajeshri G Karki, James Powers, Nello Mainolfi
|Jun 17, 2017
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.Edwige Lorthiois, Karen Anderson, Anna Vulpetti
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Frequent Collaborators
2 joint publications
Rajeshri G Karki
2 joint publications
Upendra A Argikar
2 joint publications
Anna Vulpetti
2 joint publications
Christopher M Adams
1 joint publications
James Roache
1 joint publications
Eva Altmann
1 joint publications
Kim S Beyer
1 joint publications
Andrea Vaupel
1 joint publications
Rowan Stringer
1 joint publications
Andreas Weiss
