Rajeshri G Karki

8PUBLICATIONS
27CO-AUTHORS
Proteins and peptidesGene and molecular therapyBiomolecular modelling and designBiomechanical engineeringMedical infection agents (incl. prions)
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (8)

|Feb 09, 2026
Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor.

Julien P N Papillon, Jun Yuan, Matthew J Hesse

|Jul 03, 2023
Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.

Simone Bonazzi, Audrey Gray, Noel M Thomsen

|Jun 20, 2020
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.

Edwige Lorthiois, James Roache, David Barnes-Seeman

|Feb 20, 2020
Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.

Nello Mainolfi, Takeru Ehara, Rajeshri G Karki

|Jan 21, 2020
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.

Simone Bonazzi, Carleton P Goold, Audrey Gray

|Jan 17, 2020
Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.

Dirksen E Bussiere, Lili Xie, Honnappa Srinivas

Pageof 2

Frequent Collaborators

3 joint publications

Christopher M Adams

3 joint publications

Viktor Hornak

2 joint publications

Upendra A Argikar

2 joint publications

Edwige Lorthiois