Jon Winter-Holt

9PUBLICATIONS
35CO-AUTHORS
Biologically active moleculesMolecular targetsProteomics and intermolecular interactions (excl. medical proteomics)Medical infection agents (incl. prions)Biomolecular modelling and design
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Publications (9)

|Oct 23, 2026
Discovery of a Novel Series of Benzimidazoles/Purines as Potent, Selective and Orally Active Inhibitors of the DNA Polymerase Activity of POLQ.

|Mar 30, 2026
Targeting the Interaction of NRF2 and β-TrCP with Molecular Glues.

Daniel H O Donovan, Jon Winter-Holt, Gavin W Collie

|Mar 27, 2026
Structural Studies of βTrCP Reveal Plasticity in Binding Modes of Consensus and Nonconsensus Degrons.

Gavin W Collie, Hazel Mak, Marta Acebrón-García-de-Eulate

|Jul 31, 2024
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.

James M Smith, Bernard Barlaam, David Beattie

|Jul 17, 2024
Fragment-Based Discovery of Novel MUS81 Inhibitors.

Gavin W Collie, Ulf Börjesson, Yunhua Chen

|May 09, 2022
Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems.

Beth Williamson, Lindsay McMurray, Scott Boyd

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Frequent Collaborators

4 joint publications

Gavin W Collie

3 joint publications

Maxime Couturier

3 joint publications

Argyrides Argyrou

3 joint publications

Daniel H O Donovan