Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Kevin J Filipski

4PUBLICATIONS

17CO-AUTHORS

Molecular medicineElectrochemical energy storage and conversionCell development, proliferation and deathBiologically active molecules

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (4)

Sort by Publication Date:

|Nov 19, 2024

Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948.

Kevin J Filipski, Luis A Martinez-Alsina, Matthew R Reese

|Oct 18, 2023

Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life.

Kevin J Filipski, David J Edmonds, Michelle R Garnsey

|Aug 09, 2023

Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.

Rachel J Roth Flach, Eliza Bollinger, Allan R Reyes

|Feb 22, 2018

Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK).

David J Edmonds, Daniel W Kung, Amit S Kalgutkar

Pageof 1

Frequent Collaborators

2 joint publications

David J Edmonds

2 joint publications

John Knafels

2 joint publications

Christine C Orozco

2 joint publications

Amit S Kalgutkar

1 joint publications

Daniel W Kung

1 joint publications

Aaron C Smith

1 joint publications

Yuan Zhang

1 joint publications

Bethany L Kormos

1 joint publications

Shenping Liu

1 joint publications

Matthew R Reese

Frequent Collaborators

2 joint publications

David J Edmonds

2 joint publications

John Knafels

2 joint publications

Christine C Orozco

2 joint publications

Amit S Kalgutkar

Top Related Videos

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Published on : Oct 23, 2019

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on : Nov 09, 2020

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on : Oct 26, 2015

See more related videos

Top Related Videos

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Published on : Oct 23, 2019

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on : Nov 09, 2020

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on : Oct 26, 2015

See more related videos