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David J Edmonds

7PUBLICATIONS
30CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Electrochemical energy storage and conversionDevelopmental genetics (incl. sex determination)PharmacogenomicsMolecular targets
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Journal

Publications (7)

Sort by Publication Date:
|Jan 02, 2025
Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants.

Michelle R Garnsey, Yang Wang, David J Edmonds

|Oct 18, 2023
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life.

Kevin J Filipski, David J Edmonds, Michelle R Garnsey

|Aug 24, 2023
Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.

Shenping Liu, Ruth F Sommese, Nicole L Nedoma

|Sep 28, 2020
Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs.

David A Tess, Heather Eng, Amit S Kalgutkar

|Aug 19, 2020
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.

Kim Huard, Aaron C Smith, Gregg Cappon

|Jul 24, 2018
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).

Tim F Ryder, Matthew F Calabrese, Gregory S Walker

Pageof 2

Frequent Collaborators

3 joint publications

Amit S Kalgutkar

3 joint publications

Michelle R Garnsey

2 joint publications

Daniel W Kung

2 joint publications

Kevin J Filipski

2 joint publications

Aaron C Smith

2 joint publications

Michelle F Clasquin

2 joint publications

Manthena V Varma

2 joint publications

Shenping Liu

2 joint publications

Nicole L Nedoma

1 joint publications

Robert L Dow

Frequent Collaborators

3 joint publications

Amit S Kalgutkar

3 joint publications

Michelle R Garnsey

2 joint publications

Daniel W Kung

2 joint publications

Kevin J Filipski

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