Aaron C Smith

7PUBLICATIONS
25CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsBiologically active moleculesOrganic chemical synthesisFood properties (incl. characteristics and health benefits)
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|Sep 26, 2023
Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors.

Chris Limberakis, Aaron C Smith, Scott W Bagley

|Feb 21, 2023
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss.

Michelle R Garnsey, Aaron C Smith, Jana Polivkova

|Feb 24, 2022
Decarbonylative Pd-Catalyzed Suzuki Cross-Coupling for the Synthesis of Structurally Diverse Heterobiaryls.

Alejandro Cervantes-Reyes, Aaron C Smith, Gary M Chinigo

|Aug 09, 2021
Synthesis of α-Heteroaryl Propionic Esters by Palladium-Catalyzed α-Heteroarylation of Silyl Ketene Acetals.

Bowen Li, Bangke Luo, Caroline A Blakemore

|Sep 10, 2020
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.

Kentaro Futatsugi, Aaron C Smith, Meihua Tu

|Aug 19, 2020
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.

Kim Huard, Aaron C Smith, Gregg Cappon

Pageof 2

Frequent Collaborators

3 joint publications

Daniel W Kung

2 joint publications

David J Edmonds

2 joint publications

Amit S Kalgutkar

2 joint publications

Scott W Bagley