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Rui Xu

4PUBLICATIONS

57CO-AUTHORS

Molecular targetsFlight dynamics

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Publications (4)

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|Mar 06, 2026

Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Jun 12, 2025

BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.

Dhirendra K Simanshu, Rui Xu, James P Stice

|Dec 06, 2024

Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.

Anna E Maciag, James P Stice, Bin Wang

|Jul 09, 2019

3-[(1<i>S</i>,2<i>S</i>,3<i>R</i>)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma.

Rui Xu, Keshi Wang, James P Rizzi

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Frequent Collaborators

3 joint publications

Andrew G Stephen

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James P Stice

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Bin Wang

3 joint publications

David M Turner

3 joint publications

Ken Lin

3 joint publications

Dana Rabara

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Dhirendra K Simanshu

3 joint publications

Yue Yang

3 joint publications

Felice C Lightstone

3 joint publications

Erik K Larsen

Frequent Collaborators

3 joint publications

Andrew G Stephen

3 joint publications

James P Stice

3 joint publications

Bin Wang

3 joint publications

David M Turner

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