Rui Xu

4PUBLICATIONS
57CO-AUTHORS
Molecular targetsFlight dynamics
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Publications (4)

|Mar 06, 2026
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Jun 12, 2025
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.

Dhirendra K Simanshu, Rui Xu, James P Stice

|Dec 06, 2024
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.

Anna E Maciag, James P Stice, Bin Wang

|Jul 09, 2019
3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma.

Rui Xu, Keshi Wang, James P Rizzi

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Frequent Collaborators

3 joint publications

Andrew G Stephen

3 joint publications

James P Stice

3 joint publications

Bin Wang

3 joint publications

David M Turner