Andrew G Stephen
13PUBLICATIONS
111CO-AUTHORS
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Publications (13)
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|Mar 06, 2026
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan
|Nov 24, 2025
How KRAS Mutations Impair Intrinsic GTP Hydrolysis: Experimental and Computational Investigations.Lin Frank Song, Dana Rabara, Semiha K Bali
|Sep 15, 2025
An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state.Daniel A Ritt, David E Durrant, Matthew R Drew
|Jun 12, 2025
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.Dhirendra K Simanshu, Rui Xu, James P Stice
|May 09, 2025
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.Anna E Maciag, Yue Yang, Alok K Sharma
|Dec 06, 2024
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.Anna E Maciag, James P Stice, Bin Wang
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Frequent Collaborators
10 joint publications
Dhirendra K Simanshu
9 joint publications
Frank McCormick
9 joint publications
Dwight V Nissley
7 joint publications
Dominic Esposito
4 joint publications
Timothy H Tran
4 joint publications
Simon Messing
4 joint publications
Patrick Alexander
3 joint publications
Bin Wang
3 joint publications
Anna E Maciag
3 joint publications
James P Stice
