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Patrick Alexander

4PUBLICATIONS

71CO-AUTHORS

Molecular targetsReceptors and membrane biology

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Publications (4)

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|Mar 06, 2026

Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Dec 06, 2024

Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.

Anna E Maciag, James P Stice, Bin Wang

|Jun 23, 2021

Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction.

David E Durrant, Emily A Smith, Ekaterina I Goncharova

|Sep 11, 2020

Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane.

Que N Van, Cesar A López, Marco Tonelli

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Frequent Collaborators

4 joint publications

Andrew G Stephen

3 joint publications

Dhirendra K Simanshu

3 joint publications

Dwight V Nissley

3 joint publications

Frank McCormick

2 joint publications

James P Stice

2 joint publications

Bin Wang

2 joint publications

Alok K Sharma

2 joint publications

Albert H Chan

2 joint publications

Saman Setoodeh

2 joint publications

Yue Yang

Frequent Collaborators

4 joint publications

Andrew G Stephen

3 joint publications

Dhirendra K Simanshu

3 joint publications

Dwight V Nissley

3 joint publications

Frank McCormick

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