Frank McCormick

38PUBLICATIONS

205CO-AUTHORS

Neurology and neuromuscular diseasesMolecular targetsBiomolecular modelling and designChemical engineering designCancer therapy (excl. chemotherapy and radiation therapy)

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Publications (38)

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|May 27, 2026

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions.

|Apr 22, 2026

Revisiting RAS family GTPase signaling: effector selectivity and oncogenic bypass.

|Apr 04, 2026

The heart of the matter: a personal view of Fred Wittinghofer's contributions to RAS biology and drug design.

Frank McCormick

|Mar 30, 2026

Disulfide tethering reveals cryptic pockets in oncogenic KRAS.

Trent E Balius, Marcin Dyba, Vandana Kumari

|Mar 06, 2026

Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Jan 10, 2026

Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.

Daniel A Bonsor, Lorenzo I Finci, Jacob R Potter

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Frequent Collaborators

19 joint publications

Dhirendra K Simanshu

16 joint publications

Dwight V Nissley

13 joint publications

Dominic Esposito

Andrew G Stephen

Simon Messing

Pau Castel

Antonio Cuevas-Navarro

4 joint publications

Lucy C Young

4 joint publications

Anna E Maciag

4 joint publications

Vanessa Wall

Frequent Collaborators

19 joint publications

Dhirendra K Simanshu

16 joint publications

Dwight V Nissley

13 joint publications

Dominic Esposito

9 joint publications

Andrew G Stephen