Dwight V Nissley

28PUBLICATIONS
129CO-AUTHORS
Molecular targetsBiomolecular modelling and designComputational methods in fluid flow, heat and mass transfer (incl. computational fluid dynamics)Cancer therapy (excl. chemotherapy and radiation therapy)Translational and applied bioinformatics
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Publications (28)

|Apr 21, 2026
Free Energy and Flexibility Analysis of Autoinhibited Human BRAF.

|Mar 30, 2026
Disulfide tethering reveals cryptic pockets in oncogenic KRAS.

Trent E Balius, Marcin Dyba, Vandana Kumari

|Mar 06, 2026
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Jan 10, 2026
Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.

Daniel A Bonsor, Lorenzo I Finci, Jacob R Potter

|Nov 10, 2025
Integrating Ultra-Coarse-Grained Protein Models into Accessible Workflows for Multiscale Molecular Dynamics.

Bryce Tu Chi, Stephanie Fulcar, Jonathan Ipe

|Sep 15, 2025
An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state.

Daniel A Ritt, David E Durrant, Matthew R Drew

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Frequent Collaborators

16 joint publications

Frank McCormick

15 joint publications

Dhirendra K Simanshu

14 joint publications

Dominic Esposito

9 joint publications

Andrew G Stephen