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Albert H Chan

6PUBLICATIONS

66CO-AUTHORS

Molecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Gene and molecular therapyMedical molecular engineering of nucleic acids and proteins

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Publications (6)

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|Mar 06, 2026

Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants.

Carlos Stahlhut, Anna E Maciag, Kyle A Sullivan

|Sep 11, 2025

Structural basis for LZTR1 recognition of RAS GTPases for degradation.

Srisathiyanarayanan Dharmaiah, Daniel A Bonsor, Stephanie P Mo

|May 09, 2025

Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.

Anna E Maciag, Yue Yang, Alok K Sharma

|Dec 06, 2024

Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C.

Anna E Maciag, James P Stice, Bin Wang

|Oct 20, 2023

Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise.

Klarissa Hollander, Albert H Chan, Kathleen M Frey

|Feb 05, 2017

NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.

Albert H Chan, Sung Wook Yi, Ethan M Weiner

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Frequent Collaborators

4 joint publications

Dwight V Nissley

4 joint publications

Dhirendra K Simanshu

3 joint publications

Dominic Esposito

3 joint publications

Andrew G Stephen

3 joint publications

Anna E Maciag

3 joint publications

Frank McCormick

2 joint publications

Zuhui Zhang

2 joint publications

Saman Setoodeh

2 joint publications

James P Stice

2 joint publications

Ken Lin

Frequent Collaborators

4 joint publications

Dwight V Nissley

4 joint publications

Dhirendra K Simanshu

3 joint publications

Dominic Esposito

3 joint publications

Andrew G Stephen

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