Claire McWhirter

6PUBLICATIONS
44CO-AUTHORS
Molecular targetsCheminformatics and quantitative structure-activity relationshipsCharacterisation of biological macromolecules
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Publications (6)

|Jul 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.

|Dec 08, 2025
Discovery of ART5537: A Potent and Selective Small-Molecule Probe for EXO1.

Sam E Mann, Owen A Davis, Jörg Bomke

|Sep 17, 2025
Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor.

Sam E Mann, Julien Lefranc, Omar Alkhatib

|Oct 06, 2022
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.

Martin L Stockley, Amanda Ferdinand, Giovanni Benedetti

|Jun 18, 2021
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.

Diana Zatreanu, Helen M R Robinson, Omar Alkhatib

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Frequent Collaborators

5 joint publications

Robert A Heald

4 joint publications

Eeson Rajendra

3 joint publications

Diego Grande

3 joint publications

Mark D Charles