Diego Grande

4PUBLICATIONS
52CO-AUTHORS
Molecular targetsRadiation therapyCharacterisation of biological macromolecules
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Publications (4)

|Jul 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.

|Dec 08, 2025
Discovery of ART5537: A Potent and Selective Small-Molecule Probe for EXO1.

Sam E Mann, Owen A Davis, Jörg Bomke

|Jan 23, 2023
Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.

Gonzalo Rodriguez-Berriguete, Marco Ranzani, Remko Prevo

|Jun 18, 2021
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.

Diana Zatreanu, Helen M R Robinson, Omar Alkhatib

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Frequent Collaborators

4 joint publications

Eeson Rajendra

3 joint publications

Claire McWhirter

3 joint publications

Robert A Heald

3 joint publications

Graeme C M Smith