Simon J Boulton

19PUBLICATIONS
113CO-AUTHORS
Molecular targetsGenome structure and regulationRadiation therapyCharacterisation of biological macromoleculesChemical and thermal processes in energy and combustion
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Publications (19)

|Jul 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.

|Jul 01, 2026
Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity.

|May 25, 2026
H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomas.

|Jan 09, 2026
RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress.

Tyler H Stanage, Shudong Li, Sandra Segura-Bayona

|Nov 06, 2025
Cryo-electron microscopic visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2.

Luke A Greenhough, Lorenzo Galanti, Chih-Chao Liang

|Sep 26, 2025
EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.

Marija Maric, Sandra Segura-Bayona, Raviprasad Kuthethur

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Frequent Collaborators

3 joint publications

Sandra Segura-Bayona

3 joint publications

Stephen C West

3 joint publications

Tyler H Stanage

2 joint publications

Diego Grande