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Valentin R Wydra

5PUBLICATIONS
19CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsProteins and peptides
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Journal

Publications (5)

Sort by Publication Date:
|Aug 11, 2025
Design, Synthesis, and Molecular Evaluation of S<sub>N</sub>Ar-Reactive N-(6-Fluoro-3-Nitropyridin-2-yl)Isoquinolin-3-Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode.

Larissa N Ernst, Jason Stahlecker, Finn Mier

|May 22, 2025
A "Ligand First" Approach toward Selective, Covalent JNK2/3 Inhibitors.

Valentin R Wydra, Nicole Plank, Stefan Zwirner

|Apr 01, 2025
Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP.

Larissa N Ernst, Simon J Jaag, Valentin R Wydra

|Dec 24, 2024
Probing the Protein Kinases' Cysteinome by Covalent Fragments.

Guiqun Wang, Nico J Seidler, Sandra Röhm

|Jul 28, 2023
A patent review of MAPK inhibitors (2018 - present).

Valentin R Wydra, Raphael B Ditzinger, Nico J Seidler

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Frequent Collaborators

3 joint publications

Nico J Seidler

3 joint publications

Stefan Laufer

3 joint publications

Michael Lämmerhofer

3 joint publications

Matthias Gehringer

3 joint publications

Benedikt Masberg

2 joint publications

Frank M Boeckler

2 joint publications

Ricardo A M Serafim

2 joint publications

Larissa N Ernst

2 joint publications

Simon J Jaag

2 joint publications

Cornelius Knappe

Frequent Collaborators

3 joint publications

Nico J Seidler

3 joint publications

Stefan Laufer

3 joint publications

Michael Lämmerhofer

3 joint publications

Matthias Gehringer

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