Cornelius Knappe

3PUBLICATIONS
15CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsProteins and peptides
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (3)

Sort by Publication Date:
|Aug 11, 2025
Design, Synthesis, and Molecular Evaluation of SNAr-Reactive N-(6-Fluoro-3-Nitropyridin-2-yl)Isoquinolin-3-Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode.

Larissa N Ernst, Jason Stahlecker, Finn Mier

|Jul 02, 2025
SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes.

Theresa Klett, Jason Stahlecker, Martin Schwer

|Apr 01, 2025
Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP.

Larissa N Ernst, Simon J Jaag, Valentin R Wydra

Pageof 1

Frequent Collaborators

3 joint publications

Simon J Jaag

3 joint publications

Benedikt Masberg

3 joint publications

Michael Lämmerhofer

3 joint publications

Frank M Boeckler

2 joint publications

Larissa N Ernst

2 joint publications

Valentin R Wydra

2 joint publications

Ricardo A M Serafim

2 joint publications

Thilo Stehle

2 joint publications

Matthias Gehringer

2 joint publications

Jason Stahlecker

Frequent Collaborators

3 joint publications

Simon J Jaag

3 joint publications

Benedikt Masberg

3 joint publications

Michael Lämmerhofer

3 joint publications

Frank M Boeckler

JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us

Top Related Videos

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on : Oct 26, 2015

11.4K
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
05:17

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on : Feb 09, 2021

1.6K
Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase
09:51

Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase

Published on : Jun 30, 2023

719
See more related videos

Top Related Videos

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on : Oct 26, 2015

11.4K
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
05:17

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on : Feb 09, 2021

1.6K
Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase
09:51

Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase

Published on : Jun 30, 2023

719
See more related videos