Benedikt Masberg

13PUBLICATIONS
36CO-AUTHORS
Pharmacology and pharmaceutical sciences not elsewhere classifiedMolecular targetsCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designProteins and peptides
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Publications (13)

|Aug 13, 2026
False Friends in Fluorescence - Simple HPLC Evaluation of False Positive Fragment Hits in a DiFMUP Assay for Protein Tyrosine Phosphatase 1B.

|May 16, 2026
Covalent drug rescue of multiple p53 mutants by stabilizing vinyl sulfone fragments hints to a specific refolding mechanism for R282W.

|Aug 11, 2025
Design, Synthesis, and Molecular Evaluation of SNAr-Reactive N-(6-Fluoro-3-Nitropyridin-2-yl)Isoquinolin-3-Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode.

Larissa N Ernst, Jason Stahlecker, Finn Mier

|Aug 04, 2025
A twist in the tale: shifting from covalent targeting of a tyrosine in JAK3 to a lysine in MK2.

Laura Hillebrand, Guiqun Wang, Alexander Rasch

|Jul 02, 2025
SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes.

Theresa Klett, Jason Stahlecker, Martin Schwer

|May 22, 2025
A "Ligand First" Approach toward Selective, Covalent JNK2/3 Inhibitors.

Valentin R Wydra, Nicole Plank, Stefan Zwirner

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Frequent Collaborators

12 joint publications

Michael Lämmerhofer

7 joint publications

Frank M Boeckler

4 joint publications

Jason Stahlecker

4 joint publications

Theresa Klett