[Primary malignant lymphoma of the ureter: a case report]

Hiromitsu Fujisawa1, Hiroshi Takagane, Kenji Shimosegawa

  • 1Department of Urology, Iwate Prefectural Miyako Hospital.

Insights

A rare case of ureteral non-Hodgkin lymphoma (NHL) was initially misdiagnosed as transitional cell carcinoma. This large B-cell lymphoma was successfully treated with chemotherapy, with the patient remaining disease-free for 15 months.

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Ureteral tumors are rare, with transitional cell carcinoma being the most common malignancy.
  • Accurate diagnosis is crucial for appropriate treatment and patient outcomes.

Observation:

  • A 58-year-old man presented with right hydronephrosis, revealing a ureteral mass on imaging.
  • Initial urine cytology suggested transitional cell carcinoma, leading to nephro-ureterectomy and partial cystectomy.
  • Histopathology confirmed non-Hodgkin lymphoma (large B-cell type) of the ureter, classified as Clinical Stage IE.

Findings:

  • The patient received one course of systemic chemotherapy (THP-cop) but experienced severe thrombocytopenia.
  • Despite treatment limitations, no recurrence was observed 15 months post-operation.

Implications:

  • This case highlights the importance of thorough histopathological examination to differentiate ureteral malignancies.
  • Non-Hodgkin lymphoma of the ureter, though rare, can be managed effectively, even with treatment complications.
  • Further research into optimal chemotherapy regimens for ureteral lymphoma is warranted.