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Updated: Aug 15, 2026

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
Published on: July 22, 2011
[The interpretation of laboratory parameters in evaluating the immune status of man]
Insights
Assessing patient immunity involves evaluating immunocyte activation, proliferation, and differentiation. Novel immunobiotechnology simplifies the interpretation of human immune system studies, focusing on lymphocytes and other key immune cells.
Area of Science:
- Immunology
- Biotechnology
Context:
- Assessing patient immunity is crucial for disease management.
- Current methods for evaluating immune status can be complex.
Purpose:
- To identify key physiologic parameters for assessing patient immunity.
- To introduce novel immunobiotechnology for simplified immune status evaluation.
Summary:
- Three physiologic parameters—immunocyte activation, proliferation, and differentiation—are key for assessing immunity.
- Novel immunobiotechnology enables direct examination of these parameters.
- The approach simplifies interpretation of human immune system studies, including lymphocytes, monocytes, macrophages, and granulocytes.
Impact:
- Simplifies the interpretation of immune status assessments.
- Highlights the role of various immune cells (lymphocytes, monocytes, macrophages, granulocytes) in disease pathogenesis.
- Provides a foundation for improved diagnostics and understanding of immune-related diseases.
Abstract:
At least 3 physiologic parameters appear to be useful for the assessment of the immunity status of a patient. These parameters are as follows: immunocyte ability to activation, proliferation, and differentiation; these characteristics may be directly examined with the use of novel products of immunobiotechnology. The suggested approach essentially simplifies interpretation of the findings obtained in studies of human immunity system. Besides lymphocytes, special attention is paid to immunoregulatory monocytes, macrophages, and granulocytes. Since these cells are known to secrete quite a number of mediators, an imbalance of their production and reception may contribute to the pathogenesis of many a disease.

