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Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
Published on: May 20, 2016
[Tumor and pulmonary cysts - Lice, fleas or both?]
M Simon1, R Hörster, K Dalhoff
1Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland. martin.simon@uksh.de
Insights
A 60-year-old diabetic patient presented with respiratory symptoms and was diagnosed with pulmonary adenocarcinoma. Imaging revealed widespread cystic lesions, identified as metastases, not primary lung disease.
Area of Science:
- Oncology
- Pulmonology
- Radiology
Background:
- Presents a challenging case of a 60-year-old female with insulin-dependent diabetes mellitus.
- Patient exhibited symptoms including coughing, chest pain, and low-grade fever.
Observation:
- Physical examination revealed bilateral vesicular breath sounds.
- Laboratory tests indicated slightly elevated infection parameters.
Findings:
- Diagnostic imaging, including chest X-ray and contrast-enhanced CT, identified pulmonary adenocarcinoma.
- Widespread bilateral pulmonary cystic lesions were observed, interpreted as cystic metastases.
Implications:
- Distinguishing cystic metastases from primary cystic lung disease is crucial in oncology.
- This case highlights the importance of comprehensive diagnostic work-up in complex presentations.
Abstract:
The article reports on a 60-year-old female patient with insulin-dependent diabetes who presented with coughing, chest pains and low-grade fever. Auscultation revealed a vesicular breathing noise bilaterally and the laboratory results showed slightly increased infection parameters. The initial diagnostic work-up included chest x-ray and contrast-enhanced computed tomography (CT). The diagnostics resulted in a pulmonary adenocarcinoma with osseous and hepatic metastases. Furthermore, widespread bilateral pulmonary cystic lesions were observed. Regarding the wide spectrum of differential diagnoses and the clinical pattern, the findings have to be regarded as cystic metastases and not as primary cystic lung disease.
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