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Langerhans cell histiocytosis with thyroid involvement in a 3 year-old child - a case report

Pantea Tajik1, Shiva Nazari, Hazhir Javaherizadeh

  • 1Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Polski Przeglad Chirurgiczny
|September 19, 2012
PubMed

Insights

Langerhans cell histiocytosis (LCH) rarely affects the thyroid. This case highlights LCH as a rare cause of neck masses in children, emphasizing the need for pulmonary evaluation.

Area of Science:

  • Pediatric Endocrinology
  • Oncology
  • Histiocytic Disorders

Background:

  • Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder of specific dendritic cells.
  • While LCH can affect multiple organ systems, primary thyroid involvement is exceptionally uncommon.

Observation:

  • This report details an extremely rare case of LCH primarily involving the thyroid gland in a 3-year-old boy.
  • The child presented with a persistent neck mass over several weeks.

Findings:

  • The case underscores that LCH should be considered in the differential diagnosis of pediatric thyroid masses.
  • Thyroid LCH represents a rare but significant presentation of this histiocytic disease.

Implications:

  • Early consideration of LCH in children with thyroid masses is crucial for timely diagnosis and management.
  • Pulmonary examinations are recommended for patients diagnosed with thyroid LCH due to potential systemic involvement.

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