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Incisional Hernia After Midline Versus Transverse Specimen Extraction Incision: A Randomized Trial in Patients
Lawrence Lee1,2, Juan Mata1, Raoul A Droeser1
1Steinberg-Bernstein Centre for Minimally Invasive Surgery and Innovation, McGill University Health Centre, Montreal, Quebec, Canada.
Insights
A transverse specimen extraction site in laparoscopic colectomy may reduce incisional hernia (IH) risk compared to midline incisions, particularly with longer follow-up. However, midline incisions may offer better cosmetic outcomes.
Area of Science:
- Gastrointestinal Surgery
- Minimally Invasive Surgery
- Surgical Oncology
Background:
- Midline incisions are common for specimen extraction in laparoscopic colectomy but are associated with a high risk of incisional hernia (IH).
- Transverse incisions are an alternative that may potentially lower the incidence of IH.
Purpose of the Study:
- To compare the incidence of incisional hernia (IH) between midline and transverse specimen extraction sites in patients undergoing laparoscopic colectomy.
- To evaluate secondary outcomes including perioperative parameters, pain, quality of life, and cosmesis.
Main Methods:
- A single-center, randomized superiority trial involving patients undergoing laparoscopic colectomy.
- Patients were randomly assigned to either a midline or transverse specimen extraction site.
- Primary outcome was IH incidence at 1 year, with secondary outcomes assessed using validated questionnaires.
Main Results:
- No significant difference in IH incidence was observed between transverse and midline sites on intention-to-treat analysis at 1 year (2% vs. 8%) or longer follow-up (6% vs. 14%).
- Per-protocol analysis revealed a significantly lower IH incidence for transverse sites (2%) compared to midline (15%) with longer follow-up (P=0.013).
- Quality of life scores related to body pain and social functioning improved with transverse incisions, while midline incisions showed better cosmesis without impacting body image.
Conclusions:
- Per-protocol analysis suggests transverse specimen extraction sites may lead to a lower incidence of incisional hernias compared to midline sites, especially with extended follow-up.
- Midline incisions may offer superior cosmetic results, though this does not significantly affect body image.
- The choice of incision site involves balancing the risk of incisional hernia with cosmetic considerations.
Objective:
To compare the incidence of incisional hernia (IH) between midline and transverse specimen extraction site in patients undergoing laparoscopic colectomy.
Background:
Midline specimen extraction incision is most commonly used in laparoscopic colectomy, but has high IH risk. IH may be lower for transverse incision.
Methods:
A single-center superiority trial was conducted. Eligible patients undergoing laparoscopic colectomy were randomly assigned to midline or transverse specimen extraction. Primary outcome was IH incidence at 1 year. Power calculation required 76 patients per group to detect a reduction in IH from 20% to 5%. Secondary outcomes included perioperative outcomes, pain scores, health-related quality of life (SF-36), and cosmesis (Body Image Questionnaire).
Results:
A total of 165 patients were randomly assigned to transverse (n = 79) or midline (n = 86) specimen extraction site, of which 141 completed 1-year follow-up (68 transverse, 73 midline). Patient, tumor, surgical data, and perioperative morbidity were similar. Pain scores were similar on each postoperative day. On intention-to-treat analysis, there was no difference in the incidence of IH at 1 year (transverse 2% vs midline 8%, P = 0.065) or after mean 30.3 month (standard deviation 9.4) follow-up (6% vs 14%, P = 0.121). On per-protocol analysis there were more IH after midline incision with longer follow-up (15% vs 2%, P = 0.013). On intention-to-treat analysis, SF-36 domains body pain and social functioning were improved after transverse incision. Cosmesis was higher after midline incision on per-protocol analysis, but without affecting body image.
Conclusions:
Per-protocol analysis of this trial demonstrates that a transverse specimen extraction site has a lower incidence of IH compared to midline with longer follow-up but has worse cosmesis.
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