Ras C-terminal enzimas de procesamiento - nuevos objetivos farmacológicos?

Farnesyl:protein transferase inhibitors as potential agents for the management of human prostate cancer.

Prostate cancer and prostatic diseases·2002

Medical laser safety hazard evaluation.

Health physics·2002

Design and biological activity of (S)-4-(5-([1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl)imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency.

Journal of medicinal chemistry·2001

Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.

Bioorganic & medicinal chemistry letters·2001

Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS.

Radiation research·2000

Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.

Cancer research·2000

A spliceosome-independent eukaryote generated by complete intron removal.

Cell·2026

Recent advances in Alzheimer's disease: From molecular mechanisms to therapeutic strategies.

Cell·2026

Bridging omics and physiology to build multimodal clocks of human aging.

Cell·2026

Rewriting Duchenne muscular dystrophy therapy.

Cell·2026

Photosynthetic medicine: Engineering a plant-derived nanofoundry to power mammalian cells.

Cell·2026

Map of spiking activity underlying change detection in the mouse visual system.

Cell·2026

Cuproptosis-related Gene SLC31A1 Correlates with M2 Macrophage Infiltration and Serves as a Potential Therapeutic Target in Glioma: A Comprehensive Analysis of 1573 Samples from TCGA and CGGA Databases.

Recent patents on anti-cancer drug discovery·2026

Statistical analysis plan considerations for autologous cell and cell-based gene therapy clinical trials.

Journal of biopharmaceutical statistics·2026

Designs of the clinical trials aiming at evaluating cell and gene therapy products: A critical appraisal from a literature review.

Molecular therapy. Advances·2026

Longitudinal drug response assessment of tumor organoids based on optical attenuation coefficient and multi-dimensional morphological characterization.

Biomedical optics express·2026

Nanosensitive optical coherence tomography to monitor corneal burn and treatment response in vivo.

Biomedical optics express·2026

Contemporary perspectives on metabolic surgery for type 2 diabetes: surgical techniques, outcomes, and complications.

Frontiers in endocrinology·2026

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Ras C-terminal enzimas de procesamiento - nuevos objetivos farmacológicos?

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Farnesyl:protein transferase inhibitors as potential agents for the management of human prostate cancer.

Medical laser safety hazard evaluation.

Design and biological activity of (S)-4-(5-([1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl)imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency.

Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.

Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS.

Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.

A spliceosome-independent eukaryote generated by complete intron removal.

Recent advances in Alzheimer's disease: From molecular mechanisms to therapeutic strategies.

Bridging omics and physiology to build multimodal clocks of human aging.

Rewriting Duchenne muscular dystrophy therapy.

Photosynthetic medicine: Engineering a plant-derived nanofoundry to power mammalian cells.

Map of spiking activity underlying change detection in the mouse visual system.

Cuproptosis-related Gene SLC31A1 Correlates with M2 Macrophage Infiltration and Serves as a Potential Therapeutic Target in Glioma: A Comprehensive Analysis of 1573 Samples from TCGA and CGGA Databases.

Statistical analysis plan considerations for autologous cell and cell-based gene therapy clinical trials.

Designs of the clinical trials aiming at evaluating cell and gene therapy products: A critical appraisal from a literature review.

Longitudinal drug response assessment of tumor organoids based on optical attenuation coefficient and multi-dimensional morphological characterization.

Nanosensitive optical coherence tomography to monitor corneal burn and treatment response in vivo.

Contemporary perspectives on metabolic surgery for type 2 diabetes: surgical techniques, outcomes, and complications.

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Ras C-terminal enzimas de procesamiento - nuevos objetivos farmacológicos?

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