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Updated: Jul 18, 2026

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
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Published on: October 7, 2011

HIV統合におけるLEDGF/p75の重要な役割

Manuel Llano1, Dyana T Saenz, Anne Meehan

  • 1Molecular Medicine Program, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

Science (New York, N.Y.)
|September 9, 2006
PubMed
まとめ

レンズ上皮由来成長因子 (LEDGF) /p75は,ヒト免疫不全ウイルス (HIV) の宿主ゲノムへの統合に不可欠です. この必須のコファクターは,ウイルスインテグラーゼをクロマチンと結びつけ,永久的なHIV貯蔵庫を確立するための重要なステップです.

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