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Updated: Jul 2, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
10:37

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30S翻訳開始複合体の構造

Angelita Simonetti1, Stefano Marzi, Alexander G Myasnikov

  • 1Institute of Genetics and of Molecular and Cellular Biology, Department of Structural Biology and Genomics, Illkirch F-67404, France.

Nature
|September 2, 2008
PubMed
まとめ

バクテリアのトランスレーション開始には,fMet-tRNA (fMet) が30S開始複合体 (30SIC) の内部で,開始因子 IF1およびIF2との相互作用によって正確に位置づけられる. この構造的な洞察は,70S初期化複合体組立とGTP水解活性化を明確にします.

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