Caenorhabditis elegans piRNAs,,

Marloes P Bagijn1, Leonard D Goldstein1, Alexandra Sapetschnig1

  • 1Gurdon Institute and Department of Biochemistry, University of Cambridge, The Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Rd, Cambridge CB2 1QN, UK.

Science (New York, N.Y.)
|June 16, 2012
PubMed
まとめ

C. elegansのPiwi相互作用RNA (piRNA) は,直接の切断ではなく,二次小RNA応答を通じて遺伝子を静止させます. これらのpiRNAはトランポゾンを標的とし,RNAの干渉を誘発することによって生殖線の完全性と生育性を確保します.

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