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Updated: Apr 28, 2026

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms
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Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms

Published on: July 7, 2011

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pH感受性カルシウムが膜を横断して漏れる構造的基礎

Yanqi Chang1, Renato Bruni1, Brian Kloss1

  • 1New York Consortium on Membrane Protein Structure, New York Structural Biology Center, New York, NY 10027, USA.

Science (New York, N.Y.)
|June 7, 2014
PubMed
まとめ

この研究は,カルシウム輸送に関与する細菌のタンパク質の構造を明らかにし,pHの変化がカルシウム漏れ活動をどのように調節するかを示しています. これらの発見は,細胞をアポトーシスから保護する関連するヒトタンパク質の機能についての洞察を提供します.

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