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核のアーキテクチャはHIV-1の統合場所の選択を決定する

Bruna Marini1, Attila Kertesz-Farkas2, Hashim Ali1

  • 1Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.

Nature
|March 4, 2015
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) は,好ましく核孔の近くに統合し,特定の活性遺伝子を標的とする. この核の位置付けは,ウイルスの遺伝子調節とHIV-1のライフサイクルにとって極めて重要です.

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