関連する実験動画

Updated: Feb 20, 2026

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling
08:38

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling

Published on: May 22, 2021

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マウスの脳における単細胞および同型特異的トランスレーションプロファイリング

Samantha L Sison1, Federico Zampa2, Eric R Kofman1

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.

Nature
|February 18, 2026
PubMed
まとめ

研究者らは,単一の脳細胞におけるmRNA翻訳を測定する新しい方法を開発し,脳機能と神経疾患の理解に不可欠な細胞タイプ特有のパターンと同型差異を明らかにしました.

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Isolation of Region-specific Microglia from One Adult Mouse Brain Hemisphere for Deep Single-cell RNA Sequencing09:49

Isolation of Region-specific Microglia from One Adult Mouse Brain Hemisphere for Deep Single-cell RNA Sequencing

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Non-Laser Capture Microscopy Approach for the Microdissection of Discrete Mouse Brain Regions for Total RNA Isolation and Downstream Next-Generation Sequencing and Gene Expression Profiling |10:06

Non-Laser Capture Microscopy Approach for the Microdissection of Discrete Mouse Brain Regions for Total RNA Isolation and Downstream Next-Generation Sequencing and Gene Expression Profiling |

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関連する概念動画

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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