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Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology
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与认知训练相关的皮质多巴胺D1受体结合的变化

Fiona McNab1, Andrea Varrone, Lars Farde

  • 1Neuropediatric Unit, Department of Woman and Child Health, Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden.

Science (New York, N.Y.)
|February 7, 2009
PubMed
概括

工作记忆训练通过改变大脑中多巴胺D1受体密度来提高认知能力. 这项研究揭示了精神活动如何改变活体受试者的大脑生物化学.

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function. They...