视神经头部在眼内压力降低玻璃眼外科手术后发生变化,使用光学一致性断层扫描
Victoria d'Azevedo Silveira1, Rodrigo Leivas Lindenmeyer1, Helena Messinger Pakter1,2
1Department of Ophthalmology, Hospital of Clinics from Porto Alegre, Porto Alegre, Brazil.
Journal of glaucoma
|June 13, 2023
概括
扫描源光学连贯性断层扫描 (SS-OCT) 在降低眼内压力 (IOP) 玻璃眼手术后检测到显著的视神经头部 (ONH) 变化. 在术后评估短期的ONH变化时,ONH杯 (HOC) 的斜面是一个有用的参数.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 玻璃眼瘤是一种渐进的视神经病变,通常通过眼内压力 (IOP) 降低手术来管理.
- 对视神经头部 (ONH) 的结构变化进行监测,对于对玻璃眼瘤进行管理至关重要.
- 扫描源光学连贯性断层扫描 (SS-OCT) 为ONH提供了先进的成像功能.
研究的目的:
- 为了评估光神经头部 (ONH) 的结构变化,使用SS-OCT在IOP降低玻璃眼手术后进行SS-OCT.
- 评估特定的ONH参数的实用性,包括ONH杯 (HOC) 的斜面,用于检测短期术后变化.
主要方法:
- 一项前性研究,包括15个眼睛,这些眼睛是患有进发性青光瘤的患者,正在接受内压降压手术.
- SS-OCT成像和视野测试在手术前进行,并在术后长达30-90天.
- 测量的关键参数包括环皮状视网膜神经纤维层,视野平均偏差,IOP,ONH杯尺寸 (长度,深度,HOC),以及布鲁赫膜开口 (BMO) 到BMO直径.
主要成果:
- 在术后观察到平均内血压的显著下降 (从20.5mmHg降至7天后的11mmHg).
- 在手术后,ONH杯 (HOC),ONH杯的深度和长度以及BMO到BMO的直径均显著下降.
- 平均HOC显著下降,表明IOP下降后视神经头部结构性变化.
结论:
- 通过SS-OCT测量的ONH杯的斜面 (HOC) 在IOP降低玻璃眼手术后显著下降.
- HOC是评估视神经头部短期结构变化的有价值的参数,可用于术后对玻璃眼患者进行评估.
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