从Iohexol瓶中多次无菌提取并没有增加污染风险
Caroline Purtill1, Manraj Dhesi2, Daniel Haber2
1Department of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA.
Pain physician
|August 3, 2023
概括
全球因COVID-19而出现的对比媒介短缺需要资源保护. 这项研究发现,从iohexol瓶中多次无菌抽取并不会增加污染风险,这表明可以安全地重复使用一次性使用的瓶子.
科学领域:
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
- 医疗保健管理的管理
背景情况:
- 全球IOHEXOL对比剂的短缺影响了外周注射.
- 与COVID-19相关的产量下降和锁定加剧了稀缺性.
- 一次性使用的iohexol瓶导致大量的浪费 (高达95%).
研究的目的:
- 为了确定从iohexol瓶中多次无菌提取是否会增加与单次提取相比的污染风险.
- 为了评估在IOHEXOL对比介质中的细菌的生存和生长.
主要方法:
- 实验性研究涉及21瓶iohexol瓶,在第一次和最后一次提取后进行了测试.
- 用于样本检测的细菌和真菌培养物和3MTM石膜TM.
- 在不同度的IOHEXOL中评估了对甲素敏感的金黄色葡萄球菌 (MSSA) 的生存/生长率.
主要成果:
- 在培养物中或在任何撤回的Petrifilms上没有观察到细菌或真菌生长.
- 随着iohexol度的增加,细菌数量显著下降.
- 在较高度的iohexol对比剂中,MSSA显示生存/生长率降低.
结论:
- 结果表明,一次性使用的iohexol瓶子可以安全地重复使用.
- 对比介质表现出温和的抗微生物特性.
- 重复使用iohexol瓶子可以节约资源,并在短缺期间降低医疗保健成本.
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