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Updated: Jul 17, 2025

Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia
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一种缓解病态的新方法?

Asmita Ghosh1, Christine Vande Velde1

  • 1Department of Neurosciences, Université de Montréal, Montreal, QC H3C 3J7, Canada; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.

Neuron
|September 7, 2023
PubMed
概括

RNA结合蛋白G3BP2与人类神经元和阿尔茨海默氏症神经元中的Tau相互作用.

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Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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