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相关概念视频

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
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相关实验视频

Updated: May 3, 2026

Validation of Nanobody and Antibody Based In Vivo Tumor Xenograft NIRF-imaging Experiments in Mice Using Ex Vivo Flow Cytometry and Microscopy
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Validation of Nanobody and Antibody Based In Vivo Tumor Xenograft NIRF-imaging Experiments in Mice Using Ex Vivo Flow Cytometry and Microscopy

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[纳米体查技术的进步]

Xiulan Tang1, Anqi Deng1, Wencong Chen1

  • 1Wenzhou Key Laboratory of Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, Zhejiang, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|February 19, 2024
PubMed
概括

本综述详细介绍了纳米体 (Nb) 的发展,包括图书馆建设,体外显示和亲和力成熟. 它提供了一个全面的指南,用于创建稳定的,特定的基于纳米体的药物和诊断剂.

科学领域:

  • 生物技术是生物技术.
  • 免疫学 免疫学 免疫学
关键词:
亲密关系成熟了,成熟了.在体外 (in vitro) 显示屏选纳米体 (Nb) 是一个纳米体.

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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

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Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology
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相关实验视频

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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
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  • 蛋白质工程是指蛋白质工程.

    • 背景情况:

    • 来自Camelidae的纳米体 (Nb) 是小的,稳定的,高度特异性的抗体碎片.
    • 它们的独特性质使隐藏的表位物能够被识别出来,从而在诊断和治疗中得到多种应用.
    • 目前用于纳米体开发的方法需要有效的选和优化策略.

    结论:

    • 这些技术的综合利用促进了基于纳米体的药物的快速开发.
    • 为生成稳定,可靠和特定的纳米体提供了一个全面的协议.
    • 能够创建基于纳米体的先进药物和诊断工具.