甲状腺癌与皮肤转移的转移
Bao Y Sciscent1, Hanel W Eberly1, Neerav Goyal1
1Department of Otolaryngology-Head and Neck Surgery, Penn State Milton S. Hershey Medical Center and Penn State College of Medicine, Hershey, PA, USA.
Ear, nose, & throat journal
|March 15, 2024
概括
甲状腺癌的皮肤转移是罕见的,但表明预后不佳. 本综述强调了这些具有挑战性的病例的人口统计,临床和生存数据.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 甲状腺癌的皮肤转移不常见,并且与预后不佳有关.
- 现有的数据仅限于病例报告,转移机制不明.
- 这项研究旨在巩固人口统计,临床和组织学发现.
研究的目的:
- 审查和报告甲状腺癌与皮肤转移的人口统计,临床和组织学特征.
- 分析发病率,常见的组织型,位置和生存结果.
主要方法:
- 通过使用Medline/PubMed,Cochrane和Scopus数据库进行了全面的文献审查,直到2023年5月.
- 提取的数据包括患者人口统计数据,甲状腺癌组织型,转移位置,转移时间和整体存活率.
- 确定了136例甲状腺癌与皮肤转移的病例.
主要成果:
- 乳头 (47.79%),毛囊 (30.15%) 和髓 (11.03%) 是最常见的组织型.
- 皮肤转移诊断时的平均年龄为63.13岁,从初次诊断开始的平均间隔为48.27个月.
- 头皮是最常见的转移部位 (n=48);可用病例的总生存时间平均为13.07个月.
结论:
- 甲状腺癌的皮肤转移,虽然很少见,但意味着预后不佳,需要高度的怀疑指数.
- 本综述提供了这些转移的最新概述,强调了它们的临床影响.
- 进一步研究甲状腺癌皮肤转移的机制和管理是有必要的.
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