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Updated: Jun 28, 2025

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哺乳动物PIWI-piRNA-目标复合体揭示了广泛和高效的目标沉默特征

Zhiqing Li1,2,3,4, Zhenzhen Li2,3,4, Yuqi Zhang3,4,5

  • 1School of Basic Medical Sciences, Fudan University, Shanghai, China.

Nature structural & molecular biology
|April 24, 2024
PubMed
概括

哺乳动物PIWI相互作用RNA (piRNA) 复合体比无脊椎动物更有效地结合和分裂目标. 在piRNA种子中的特定氨酸允许更广泛的目标沉默,增强基因组防御.

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